Sodium borohydride → HCID 20059509, compound

HRID 1086058Notes

Reaction equation

HRID 1086058 reaction equation
[NH2:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]([C:6]([NH:8][CH:9]2[CH:14]3[CH2:15][CH2:16][N:11]([CH2:12][CH2:13]3)[CH2:10]2)=[O:7])=[C:4]([O:20][CH2:21][C:22](=[O:24])[CH3:23])[CH:3]=1.[BH4-].[Na+]>C(O)C>[NH2:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]([C:6]([NH:8][CH:9]2[CH:14]3[CH2:15][CH2:16][N:11]([CH2:12][CH2:13]3)[CH2:10]2)=[O:7])=[C:4]([O:20][CH2:21][CH:22]([OH:24])[CH3:23])[CH:3]=1

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 86742916HCID 86742916, compound

Product 1

HCID 20059509HCID 20059509, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product from Example 75 is treated with sodium borohydride in absolute ethanol at reflux to give the title compound.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-02697f3cde0547d79110549ba19f6419
Source dataset
uspto-grants-1991_04
Patent number
US05011992

Reaction notes

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