HCID 178455929, compound → HCID 178476513, compound

HRID 1086119Notes

Reaction equation

HRID 1086119 reaction equation
[NH:1](C(OCC1C=CC=CC=1)=O)[C@@H:2]([C:10]([NH:12][C@H:13]([C:18]([NH:20][C@H:21]([C:26]([NH:28][C@H:29]([C:37]([NH:39][C@H:40]([C:45]([O:47]CC1C=CC=CC=1)=[O:46])[C@H:41]([CH2:43][CH3:44])[CH3:42])=[O:38])[CH2:30][CH2:31][CH2:32][NH:33][C:34](=[NH:36])[NH2:35])=[O:27])[CH2:22][CH:23]([CH3:25])[CH3:24])=[O:19])[C@H:14]([CH2:16][CH3:17])[CH3:15])=[O:11])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[NH:9])[NH2:8]>C(O)(=O)C>[NH2:1][C@@H:2]([C:10]([NH:12][C@H:13]([C:18]([NH:20][C@H:21]([C:26]([NH:28][C@H:29]([C:37]([NH:39][C@H:40]([C:45]([OH:47])=[O:46])[C@H:41]([CH2:43][CH3:44])[CH3:42])=[O:38])[CH2:30][CH2:31][CH2:32][NH:33][C:34](=[NH:35])[NH2:36])=[O:27])[CH2:22][CH:23]([CH3:24])[CH3:25])=[O:19])[C@H:14]([CH2:16][CH3:17])[CH3:15])=[O:11])[CH2:3][CH2:4][CH2:5][NH:6][C:7](=[NH:8])[NH2:9].[CH3:40][C:45]([OH:47])=[O:46].[CH3:40][C:45]([OH:47])=[O:46]

Participants

3

Reactant 1

HCID 178455929HCID 178455929, compound

Product 1

HCID 178476513HCID 178476513, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

510 mg of Z-D-Arg-Ile-Leu-Arg-Ile-OBzl are catalytically hydrogenated in 15 ml of 90% acetic acid in analogy to Example 1b.

Sources & evidence

ORD record
ord-9007c355cb11414d80419a979a15e4a4
Source dataset
uspto-grants-1991_04
Patent number
US05011825

Reaction notes

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