1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 1-Cyclopropyl-6,8-difluoro-7-[2-(formylaminomethyl)morpholino]-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
Reaction equation
[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([F:15])[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1.[CH:21](=[O:22])[NH:23][CH2:24][CH:25]1[O:26][CH2:27][CH2:28][NH:29][CH2:30]1>>[CH:1]1([n:4]2[cH:5][c:6]([C:18](=[O:19])[OH:20])[c:7](=[O:17])[c:8]3[cH:9][c:10]([F:16])[c:11]([N:29]4[CH2:28][CH2:27][O:26][CH:25]([CH2:24][NH:23][CH:21]=[O:22])[CH2:30]4)[c:12]([F:14])[c:13]23)[CH2:2][CH2:3]1Participants
3
Sources & evidence
- ORD record
- ord-d9522e9f7d004902a472c717ff9587d3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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