5-Aminoimidazole-4-carboxamide hydrochloride → HCID 178424555, compound
Reaction equation
[C:1]([CH:4]([CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][C:15](=[C:18]([C:25]2[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][CH:26]=2)[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:14][CH2:13]1)[C:5](OCC)=[O:6])(=O)[CH3:2].[ClH:32].[NH2:33][C:34]1[N:35]=[CH:36][NH:37][C:38]=1[C:39](=[O:41])[NH2:40]>>[ClH:32].[C:39]([C:38]1[N:37]=[CH:36][N:35]2[C:5]([OH:6])=[C:4]([CH2:10][CH2:11][N:12]3[CH2:13][CH2:14][C:15](=[C:18]([C:25]4[CH:26]=[CH:27][C:28]([CH3:31])=[CH:29][CH:30]=4)[C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[CH2:16][CH2:17]3)[C:1]([CH3:2])=[N:33][C:34]=12)(=[O:41])[NH2:40]Participants
3
Procedure
This compound was prepared from ethyl 2-acetyl-4-{4-[(4-methylphenyl)phenylmethylene]-1-piperidyl}-butyrate and 4-amino-5-carbamoyl imidazole hydrochloride according to the process described in Example 1.
Sources & evidence
- ORD record
- ord-13cfef90be154c518743c24cfb047300
- Source dataset
- uspto-grants-1991_07
- Patent number
- US05028607
Reaction notes
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