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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 10862Erstellt: 25. Oktober 2026

4,5-Dichlorophthalic anhydride → Ethyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate

https://huagongshe.com/reaction/10862

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4,5-Dichlorophthalic anhydrideHCID 70334—
EduktEthyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982228—
ProduktEthyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982181—

Reaktionsschritte

Ethyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.66 g, 50%) in the same manner as described in the above example 5 (20) from ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.60 g, 3.25 mmol) and 4,5-dichlorophthalic anhydride (0.85 g, 3.90 mmol), and the obtained product was identified with the following NMR data.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07094908B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-b65c8bbe15784ca3b285bbca9b865f1d
Quellennotizuspto-grants-2006_08