Tetrahydrofuran → HCID 53869832, compound

Participants

Reaction Steps

A solution of 4-(4-(2-quinolinylmethyloxy)benzyl) benzoyl chloride (0.05 mol) in tetrahydrofuran (300 ml) is added to a concentrated ammonium hydroxide (25 ml) solution and the reaction stirred overnight. The reaction mixture is evaporated and partitioned between ethyl acetate and water. The ethyl acetate fraction is dried and evaporated to give 4-(4-(2-quinolinylmethyloxy)styryl)benzamide.

Provenance & Evidence