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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1086292Generated: November 2, 2026

Thiazolidine → HCID 10449942, compound

https://huagongshe.com/reaction/1086292

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiazolidineHCID 10444—
ReactantPyrrolidineHCID 31268—
ReactantHCID 10108113HCID 10108113—
Reactant3-(2-indanylacetyl)-L-thioprolineHCID 131716918—
ProductHCID 10449942HCID 1044994252%

Reaction Steps

Colorless crystals of 1-{1-[(S)-(-)-1,2,3,4-tetrahydronaphthalen-2-ylacetyl]-L-prolyl}pyrrolidine were prepared in the same manner as in Example 1, except that 1-[(S)-(-)-1,2,3,4-tetrahydronaphthalen-2-ylacetyl]-L-proline prepared in Reference Example 28 and pyrrolidine were used instead of 3-(2-indanylacetyl)-L-thioproline and thiazolidine, respectively (yield: 52%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05028604
Source datasetuspto-grants-1991_07
ORD IDord-d44293b2f17a40e5a8eb9e296e7c3013
Source noteuspto-grants-1991_07