5-amino-3-[N-(2-mercaptoethyl)benzylamino]-1,2,4-triazole → bis{2-[N-benzyl-N-(5-amino-1,2,4-triazol-3-yl) amino]ethyl}disulfide

Participants

Reaction Steps

A mixture of 1.0 g of 5-amino-3-[N-(2-mercaptoethyl)benzylamino]-1,2,4-triazole, 20 ml of methanol and 5 mg of ferrous sulfate heptahydrate was stirred at room temperature for 16 hours. After the reaction, the resulting crystals were collected by filtration to give 0.9 g of bis{2-[N-benzyl-N-(5-amino-1,2,4-triazol-3-yl) amino]ethyl}disulfide (Compound 7).

Provenance & Evidence