反应详情

Cholesterol sulfate was converted to the free acid form by cation exchange chromatography in a methanol/chloroform/water (5:4:1) solvent. The free acid form (120 mg) was dissolved in 2 ml of chloroform, and this solution was added to a round bottom flask containing 40 mg minoxidil and 370 mg of PC. The flask was gently agitated until the components were completely dissolved. The solution was dried to a thin lipid film in a round bottom flask with rotary evaporation and lyophilization, as above. A liposome suspension was prepared as in Example 8. No minoxidil crystals were observed in the suspension.

1. additionthis solution was added to a round bottom flask
2. dissolutionwere completely dissolved
3. customThe solution was dried to a thin lipid film in a round bottom flask with rotary evaporation and lyophilization
4. customA liposome suspension was prepared as in Example 8