反应详情

22.84 g. (100 mmoles) of ethyl dodecanoate and 15.34 g. (118 mmoles) of N1 -isopropyl-2-methyl-1,2-propanediamine was heated at 130°-230° C. until approximately 100 mmoles of ethanol was collected. Toluene was then cautiously added and the heating was continued until no more water separated. The solution was acidified, the aqueous layer was separated and basified with NaOH. This was extracted with ethyl acetate, the organic extract was dried and concentrated. The oil was distilled at 150°-152° C./1.2 mm to give 16.74 g (58%) of product.

1. customwas collected
2. additionToluene was then cautiously added
3. customseparated
4. customthe aqueous layer was separated
5. extractionThis was extracted with ethyl acetate
6. extractionthe organic extract
7. customwas dried
8. concentrationconcentrated
9. distillationThe oil was distilled at 150°-152° C./1.2 mm