HCID 67830367, compound → HCID 86744892, compound

HRID 1086485Notes

Reaction equation

HRID 1086485 reaction equation
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[O:9]([CH:13]1[CH2:18]CN(C(C2CCN(C)CC2)=O)CC1)[N+:10]([O-:12])=[O:11].OC1CC[NH:32]CC1.[CH3:35][N:36]1[CH2:41][CH2:40][CH:39]([C:42]([OH:44])=O)[CH2:38][CH2:37]1>C(O)C>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[CH3:35][N:36]1[CH2:37][CH2:38][CH:39]([C:42]([NH:32][CH2:18][CH2:13][O:9][N+:10]([O-:12])=[O:11])=[O:44])[CH2:40][CH2:41]1

Participants

4

Reactant 2

HCID 67830367HCID 67830367, compoundHCID 86744893HCID 86744893, compound

Product 1

HCID 86744892HCID 86744892, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-methylpiperidine-4-carboxylic acid 4-nitroxypiperidide fumarate from 1-methyl-piperidine-4-carboxylic acid 4-hydroxypiperidine; yield 74% of theory; solvent: ethanol; m.p. 173°-175° C.

Sources & evidence

ORD record
ord-af9882bb868a4d02af937267e2c6723b
Source dataset
uspto-grants-1991_07
Patent number
US05030641

Reaction notes

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