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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1086522Generated: October 30, 2026

4-Chlorobenzenesulfonyl chloride → Methyl [2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetate

https://huagongshe.com/reaction/1086522

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzenesulfonyl chlorideHCID 7398—
Reactantmethyl (+)-(2-aminoindan-5-yl)acetate (+)-dibenzoyl-D-tartaric acid saltHCID 131716945—
ProductMethyl [2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetateHCID 53769737—

Reaction Steps

In the same manner as described in Examples 50-(1), methyl (+)-(2-aminoindan-5-yl)acetate (+)-dibenzoyl-D-tartaric acid salt and 4-chlorophenylsulfonyl chloride are treated to give methyl (+)-[2-[(4-chlorophenyl)sulfonylamino]indan-5-yl]acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05030652
Source datasetuspto-grants-1991_07
ORD IDord-0c59ca8b64d746698b8a188e98d0f254
Source noteuspto-grants-1991_07