Hydrazine → HCID 15730198, compound

HRID 1086599Notes

Reaction equation

HRID 1086599 reaction equation
[OH:1][C:2]1[C:11]([OH:12])=[CH:10][C:9]([S:13]([OH:16])(=[O:15])=[O:14])=[CH:8][C:3]=1[C:4](OC)=[O:5].[K].[NH2:18][NH2:19]>CO>[OH:1][C:2]1[C:11]([OH:12])=[CH:10][C:9]([S:13]([OH:16])(=[O:15])=[O:14])=[CH:8][C:3]=1[C:4]([NH:18][NH2:19])=[O:5]

Participants

5

Reactant 3

HCID 9321HydrazineHCID 5462222PotassiumHCID 15730197HCID 15730197, compound

Product 1

HCID 15730198HCID 15730198, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2,3-Dihydroxy-5-sulfobenzoic acid, methyl ester, monopotassium salt (2.7 g, 9.4 mmole) and neat hydrazine (0.88 ml, 28 mmoles) in 100 ml of methanol were refluxed for 48 hours. The resulting white precipitate was filtered, dried, and dissolved in water (10 ml). Acidification to pH=2.5 with 2N hydrochloric acid, filtering and drying gave 940 mg of the title compound as a solid.

Workup

  1. filtrationThe resulting white precipitate was filtered
  2. customdried
  3. dissolutiondissolved in water (10 ml)
  4. filtrationAcidification to pH=2.5 with 2N hydrochloric acid, filtering
  5. customdrying

Sources & evidence

ORD record
ord-16db1b343d4640508638e62af2c20178
Source dataset
uspto-grants-1991_07
Patent number
US05030724

Reaction notes

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