2-Bromothiazole → HCID 14100437, compound

HRID 1086610Notes

Reaction equation

HRID 1086610 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]([C:6]([NH2:8])=[O:7])[C:4]=1[NH2:12].Br[C:14]1[S:15][CH:16]=[CH:17]N=1>>[CH3:1][O:2][C:3]1[CH:11]=[CH:10][CH:9]=[C:5]2[C:4]=1[N:12]=[C:14]1[S:15][CH:16]=[CH:17][N:8]1[C:6]2=[O:7]

Participants

3

Reactant 2

HCID 764302-BromothiazoleHCID 185365712-Amino-3-methoxybenzamide

Product 1

HCID 14100437HCID 14100437, compoundYield 87.1%

Procedure

16.6 g of 3-methoxyanthranilamide and 16.4 g of 2-bromothiazole were stirred for 7 hours at 150° C. After working up in the conventional manner there was obtained 20.2 g (87%) of the above compound; m.p. 230°-232° C.

Sources & evidence

ORD record
ord-cc78c96a70cb4df1b03a3b148a1b24a8
Source dataset
uspto-grants-1991_07
Patent number
US05030727

Reaction notes

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