HRID1086772

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID225771

未命名化合物

HCID131716326

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCC=CC1CC(=O)OC1=O.NC(CO)(CO)CO.O=C1CCCCCO1

HCID131716327

未命名化合物

CONDITIONS

反应条件

温度: 180 °C

PROCEDURE

实验过程

About 87.5 g (0.25 moles) of octadecenyl succinic anhydride (OSA), 117.4 g (0.5 moles) of the CL-THAM adduct of Example 4 and 0.1 g of p-TOSH were added to a 500 ml. flask and slowly heated to 180° C. while under a nitrogen atmosphere. The reaction mixture was checked periodically by infrared analysis. At the end of the fourth hour at 180° C., while under nitrogen, the infrared analysis showed complete conversion to the desired ester oxazoline. The reaction mixture was then cooled and collected.

WORKUP

后处理

customat 180° C.
temperatureThe reaction mixture was then cooled
customcollected

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6908c21c4f5c4e86a3dc5acbe1b1ede0
来源数据集: uspto-grants-1991_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05032320
来源说明: uspto-grants-1991_07

反应 SMILES

[CH:1]([CH:19]1[CH2:24][C:23](=[O:25])[O:22][C:20]1=[O:21])=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH2:26]1[CH2:33][CH2:32][O:31][C:29](=[O:30])[CH2:28][CH2:27]1.[CH2:34]([OH:41])[C:35]([NH2:40])([CH2:38][OH:39])[CH2:36][OH:37]>>[CH:1]([CH:19]1[CH2:24][C:23](=[O:25])[O:22][C:20]1=[O:21])=[CH:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH2:26]1[CH2:33][CH2:32][O:31][C:29](=[O:30])[CH2:28][CH2:27]1.[CH2:34]([OH:41])[C:35]([NH2:40])([CH2:38][OH:39])[CH2:36][OH:37]