Dimethylformamide → HCID 178516953, compound

Participants

Reaction Steps

1.15 g of 3-carboxymethyl rhodanine and 1 g of 5-amino-2-mercaptobenzimidazole were dissolved in 25 ml of tetrahydrofuran. A solution of 1.2 g of dicyclohexyl carbodiimide in 5 ml of tetrahydrofuran was added to the solution. The mixture was then stirred at room temperature for 5 hours. The resulting precipitate was filtered off to obtain 2 g of semiopaque powder. 20 ml of N,N-dimethylformamide was added to the powder. The mixture was then stirred. Insoluble matters were filtered out. 200 ml of water was added to the filtrate. The resulting precipitate was filtered off, washed with water and then dried to obtain 1.1 g of 3-[N-(2-mercaptobenzimidazole-5-yl)carbamoyl]rhodanine in the form of semiopaque powder;

Provenance & Evidence