Methyl DL-prolinate → Methyl 1-[2-[2-amino-4-(1,3-dihydroisoindole-2-carbonyl)quinazolin-6-yl]benzoyl]pyrrolidine-2-carboxylate
Reaction equation
[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7](-[c:23]3[c:24]([C:25](=[O:26])[OH:27])[cH:28][cH:29][cH:30][cH:31]3)[cH:8][c:9]2[c:10]([C:12](=[O:13])[N:14]2[CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[CH2:22]2)[n:11]1.[NH:32]1[CH:33]([C:37](=[O:38])[O:39][CH3:40])[CH2:34][CH2:35][CH2:36]1>>[NH2:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7](-[c:23]3[c:24]([C:25](=[O:26])[N:32]4[CH:33]([C:37](=[O:38])[O:39][CH3:40])[CH2:34][CH2:35][CH2:36]4)[cH:28][cH:29][cH:30][cH:31]3)[cH:8][c:9]2[c:10]([C:12](=[O:13])[N:14]2[CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[CH2:22]2)[n:11]1Participants
3
Sources & evidence
- ORD record
- ord-d155ff2903a54f4ca56fd4d45201fe96
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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