Acetic Anhydride → 5-[1-(6-Methoxy-2-naphthyl)ethyl]-2-phenyl-4-acetoxythiazole

HRID 1086810Notes

Reaction equation

HRID 1086810 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([C:15]1[S:19][C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[N:17][C:16]=1[OH:26])[CH3:14])[CH:7]=[CH:6]2.[C:27](OC(=O)C)(=[O:29])[CH3:28]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([CH:13]([C:15]1[S:19][C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[N:17][C:16]=1[O:26][C:27](=[O:29])[CH3:28])[CH3:14])[CH:7]=[CH:6]2

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 151661295-[1-(6-Methoxy-2-naphthyl)ethyl]-2-phenyl-4-hydroxythiazole

Product 1

HCID 151661745-[1-(6-Methoxy-2-naphthyl)ethyl]-2-phenyl-4-acetoxythiazole

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The desired compound is prepared by treatment of the product of Example 5 with acetic anhydride and pyridine.

Sources & evidence

ORD record
ord-532b5d641b0b42d39e414f195ef8b56c
Source dataset
uspto-grants-1991_07
Patent number
US05032588

Reaction notes

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