Salicylic Acid → HCID 86744923, compound

Participants

Reaction Steps

To a mixture of 13.8 parts of salicylic acid, 18.4 parts of toluene, 6.9 parts of 87% paraformaldehyde and 30 parts of acetic acid was added 1.0 part of sulfuric acid (catalyst). After being heated under reflux for 4 hours, the reaction mixture was washed with water, and unreacted toluene and water were removed by vacuum distillation to give 31 parts of salicylic acid-toluene-formaldehyde co-condensation product. 10 parts of the co-condensation product was added to 41 parts of aqueous 10% sodium hydroxide solution and dissolved at 80° C. The resulting solution was cooled to 40° C., and 7.0 parts of zinc chloride was added thereto. After the reaction had been allowed to proceed at 40° C. for 1 hour, precipitates formed were collected by filtration, washed with water and then dried to give 12 parts of zinc salt of salicylic acid-toluene-formaldehyde co-condensation product.

Provenance & Evidence