2-Chloroadenosine → HCID 15036616, compound

HRID 1087008Notes

Reaction equation

HRID 1087008 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:7][CH2:8][NH2:9])[S:5][CH:6]=1.Cl[C:11]1[N:12]=[C:13]([NH2:29])[C:14]2[N:15]=[CH:16][N:17]([C:27]=2[N:28]=1)[C@@H:18]1[O:26][C@H:23]([CH2:24][OH:25])[C@@H:21]([OH:22])[C@H:19]1[OH:20]>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:7][CH2:8][NH:9][C:11]2[N:12]=[C:13]([NH2:29])[C:14]3[N:15]=[CH:16][N:17]([C:27]=3[N:28]=2)[C@@H:18]2[O:26][C@H:23]([CH2:24][OH:25])[C@@H:21]([OH:22])[C@H:19]2[OH:20])[S:5][CH:6]=1

Participants

3

Reactant 2

HCID 89742-ChloroadenosineHCID 150366152-(4-Bromothiophen-2-yl)ethan-1-amine

Product 1

HCID 15036616HCID 15036616, compound

Procedure

Condensation of 2-(4-bromo-2-thienyl)-ethylamine with 2-chloroadenosine essentially according to the procedure in the previous examples yields 2-[2-(4-bromo-2-thienyl)-ethylamino]-adenosine, melting at 136°-144°.

Sources & evidence

ORD record
ord-a1311be8d1274a25b24084b4151cf913
Source dataset
uspto-grants-1991_07
Patent number
US05034381

Reaction notes

Loading…