HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1087097Generated: October 31, 2026
Diethylamine → N,N-Diethyl-N′-nitroguanidine
https://huagongshe.com/reaction/1087097
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | N-Nitro-S-methylisothiourea | HCID 135927615 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N,N-Diethyl-N′-nitroguanidine | HCID 135794776 | 53.1% |
Reaction Steps
To a mixture of 1.35g of S-methyl-N-nitroisothiourea and 5ml of acetonitrile was added 0.88g of diethylamine, followed by stirring for 6 hours in an oil bath of 60° C. The reaction mixture was concentrated and the residue was purified by a column chromatography [developing solvent: dichloromethanemethanol (20:1)] to afford 0.85g of N,N-diethyl-N'-nitroguanidine as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05034404 |
|---|
| Source dataset | uspto-grants-1991_07 |
|---|
| ORD ID | ord-f3a14ab79f8f41a584d7f90d0538ed6e |
|---|
| Source note | uspto-grants-1991_07 |
|---|
