反应详情

温度

175 °C

A mixture of 3-(2,4-difluorophenylthio)-4-nitrobenzonitrile (3.6 g), sulfuric acid (3 ml) and water (3 ml) as stirred at 175° C. for 15 minutes. Water as added to the reaction mixture, and the mixture was extracted with ethyl acetate. The extract was dried over magnesium sulfate and evaporated to give crystals of 3-(2,4-difluorophenylthio)-4-nitrobenzoic acid (3.6 g).

1. extractionthe mixture was extracted with ethyl acetate
2. dry with materialThe extract was dried over magnesium sulfate
3. customevaporated