Sodium borohydride → HCID 10472734, compound

Participants

Reaction Steps

Sodium borohydride (0.11 g) was added portionwise to a solution of 2'-(2,4-difluorophenylthio)-4'-formylmethanesulfonanilide (1 g) in methanol (10 ml) at 10° C. The mixture was stirred at room temperature for 2 hours and evaporated. The residue was dissolved in ethyl acetate, washed with dilute hydrochloric acid and water successively, dried, and concentrated to dryness. The residue was recrystallized from ethanol to give colorless crystals of 2'-(2,4-difluorophenylthio)-4'-(hydroxymethyl)methanesulfonanilide (0.74 g).

Provenance & Evidence