HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1,2-Bis(3,4-dimethoxyphenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Veratrole | HCID 7043 | — |
| Reactant | (3,4-Dimethoxyphenyl)acetic acid | HCID 7139 | — |
| Product | 1,2-Bis(3,4-dimethoxyphenyl)ethanone | HCID 231111 | 60% |
Reaction Steps
A warm solution of 3,4-dimethoxyphenylacetic acid (10 g) in veratrole (15 ml) was added to 200 g of polyphosphoric acid (PPA). After 24 hrs. at room temperature the acid mixture was added to cold water (800 ml) and the product was collected and recrystallized from aqueous ethanol. The recrystallized intermediate (9.5 g, 60% yield) had a melting point of 104°-105°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05034544 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-39ca3b0eaeec40169d68941347309b1a |
| Source note | uspto-grants-1991_07 |