Sodium Hydroxide → HCID 53915307, compound

HRID 1087378Notes

Reaction equation

HRID 1087378 reaction equation
[H][H].[C:3]([C:7]1[CH:30]=[CH:29][C:10]2[CH2:11][CH2:12][C:13]3[CH:21]=[C:20]([CH:22]([N:24]([OH:28])[C:25]([NH2:27])=[O:26])[CH3:23])[CH:19]=[CH:18][C:14]=3[S:15](=[O:17])(=[O:16])[C:9]=2[CH:8]=1)([O:5]C)=[O:4].[OH-].[Na+]>C(O)C>[C:3]([C:7]1[CH:30]=[CH:29][C:10]2[CH2:11][CH2:12][C:13]3[CH:21]=[C:20]([CH:22]([N:24]([OH:28])[C:25]([NH2:27])=[O:26])[CH3:23])[CH:19]=[CH:18][C:14]=3[S:15](=[O:16])(=[O:17])[C:9]=2[CH:8]=1)([OH:5])=[O:4]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 19816856HCID 19816856, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 53915307HCID 53915307, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Where R1 is hydrogen and R2 is carbomethoxy, a compound of formula I, such as N-[1-(7-carbomethoxy-5,5-dioxo-10,11-dihydro dibenzo [b,f] thiepin-2-yl) ethyl]-N-hydroxy urea, may be hydrolyzed by base, such as aqueous sodium hydroxide, in an alcoholic solvent, such as ethanol to yield the N-[1-(7-carboxy-5,5-dioxo-10,11-dihydro dibenzo [b,f] thiepin-2-yl)ethyl]-N-hydroxy urea.

Sources & evidence

ORD record
ord-55640ea02d514b3e8ee763a7bbcc3c4b
Source dataset
uspto-grants-1991_07
Patent number
US05036067

Reaction notes

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