(Chloromethyl)triphenylphosphonium chloride → HCID 53874710, compound

HRID 1087400Notes

Reaction equation

HRID 1087400 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH2:18][C:19]#[CH:20])[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)=O.[Cl-].[Cl:22][CH2:23][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>>[Cl:22][CH:23]=[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)[CH:9]([CH2:18][C:19]#[CH:20])[C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1]

Participants

3

Reactant 2

HCID 197823(Chloromethyl)triphenylphosphonium chlorideHCID 19817046HCID 19817046, compound

Product 1

HCID 53874710HCID 53874710, compound

Procedure

starting from 2-(2,4-dichlorophenyl)-1-(3-pyridyl)-4-pentyn-1-one and chloromethyltriphenylphosphonium chloride there is obtained 3-[α-chloromethylene-2,4-dichloro-β-(2-propynyl)-phenethyl]-pyridine as an isomer-pure compound in the form of white crystals, m.p. 87-88° C.;

Sources & evidence

ORD record
ord-11ade9d837e64d3ba75b7694bcfcafb4
Source dataset
uspto-grants-1991_07
Patent number
US05036074

Reaction notes

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