2-(2,4-Dichlorophenyl)-1-(3-pyridyl)-4-pentyn-1-one → 3-[alpha-Butylidene-2,4-dichloro-beta-(2-propynyl)-phenethyl]-pyridine

HRID 1087401Notes

Reaction equation

HRID 1087401 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH:9]([CH2:18][C:19]#[CH:20])[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)=O>[Br-].C([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)CCC>[CH:7](=[C:10]([C:12]1[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=1)[CH:9]([CH2:18][C:19]#[CH:20])[C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 198170462-(2,4-Dichlorophenyl)-1-(3-pyridyl)-4-pentyn-1-one

Product 1

HCID 545327333-[alpha-Butylidene-2,4-dichloro-beta-(2-propynyl)-phenethyl]-pyridine

Reagents, catalysts & solvents 1

HCID 159628Butyltriphenylphosphonium bromideCatalyst

Procedure

starting from 2-(2,4-dichlorophenyl)-1-(3-pyridyl)-4-pentyn-1-one and butyltriphenylphosphonium bromide 1 there is obtained 3-[α-butylidene-2,4-dichloro-β-(2-propynyl)-phenethyl]-pyridine

Sources & evidence

ORD record
ord-a507bfe49f504ef59322be94ccf9ef2e
Source dataset
uspto-grants-1991_07
Patent number
US05036074

Reaction notes

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