反应详情

2-(Acetoxyacetylamino)-4-methoxybenzothiazole (1.0 g) prepared in Example 4 is dissolved in methanol (40 ml) and thereto is added 28% aqueous ammonia (4 ml) and the mixture is stirred at room temperature for 1 hour. The solvent is distilled off and the resulting solids are washed with water, dried and recrystallized from ethanol to give the title compound (0.7 g) having the following physical properties.

1. distillationThe solvent is distilled off
2. washthe resulting solids are washed with water
3. customdried
4. customrecrystallized from ethanol