Ammonia → HCID 15662333, compound

HRID 1087466Notes

Reaction equation

HRID 1087466 reaction equation
C([O:4][CH2:5][C:6]([NH:8][C:9]1[S:10][C:11]2[CH:17]=[CH:16][CH:15]=[C:14]([Cl:18])[C:12]=2[N:13]=1)=[O:7])(=O)C.N>CO>[Cl:18][C:14]1[C:12]2[N:13]=[C:9]([NH:8][C:6](=[O:7])[CH2:5][OH:4])[S:10][C:11]=2[CH:17]=[CH:16][CH:15]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 15662332HCID 15662332, compound

Product 1

HCID 15662333HCID 15662333, compoundYield 79.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(Acetoxyacetylamino)-4-chlorobenzothiazole (2.8 g) prepared in Example 8 is dissolved in methanol (100 ml) and thereto is added 28% aqueous ammonia (10 ml) and the mixture is stirred at room temperature for 1 hour. The solvent is distilled off and the resulting solids are washed with water, dried and recrystallized from ethanol to give the title compound (1.9 g) having the following physical properties.

Workup

  1. distillationThe solvent is distilled off
  2. washthe resulting solids are washed with water
  3. customdried
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-5202dd69d1e64985b447d0c4588f7b33
Source dataset
uspto-grants-1991_07
Patent number
US05036086

Reaction notes

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