反应详情

2-Amino-6-methylbenzothiazole (4.9 g) is dissolved in pyridine (100 ml) and thereto is added dropwise methoxyacetyl chloride (3.0 ml) at room temperature. After the mixture is stirred at room temperature for 2 hours, the solvent is distilled off. The resulting oil is solidified with addition of water. The obtained solids are filtered off and washed with water, then with diethyl ether, dried and recrystallized from ethanol to give the title compound (4.1 g) having the following physical properties.

1. distillationthe solvent is distilled off
2. additionThe resulting oil is solidified with addition of water
3. filtrationThe obtained solids are filtered off
4. washwashed with water
5. dry with materialwith diethyl ether, dried
6. customrecrystallized from ethanol