2-Amino-6-nitrobenzothiazole → HCID 733302, compound

HRID 1087473Notes

Reaction equation

HRID 1087473 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:14][O:15][CH2:16][C:17](Cl)=[O:18]>N1C=CC=CC=1>[CH3:14][O:15][CH2:16][C:17]([NH:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1)=[O:18]

Participants

4

Reactant 2

HCID 227042-Amino-6-nitrobenzothiazoleHCID 96623Methoxyacetyl chloride

Product 1

HCID 733302HCID 733302, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2-Amino-6-nitrobenzothiazole (5.9 g) is dissolved in pyridine (100 ml) and thereto is added dropwise methoxyacetyl chloride (3.0 ml) at room temperature. After the mixture is stirred at room temperature for 2 hours, the solvent is distilled off. The resulting solids are washed with water, then with diethyl ether, dried and recrystallized from ethanol to give the title compound (5.1 g) having the following physical properties.

Workup

  1. distillationthe solvent is distilled off
  2. washThe resulting solids are washed with water
  3. dry with materialwith diethyl ether, dried
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-8c8d3e4af4334ba593630192f3331624
Source dataset
uspto-grants-1991_07
Patent number
US05036086

Reaction notes

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