HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4,5,8,9-tetrahydro-8-phenyl-7H-thieno[3,2-a]quinolizin-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl 2-methylenephenylacetate | HCID 19020437 | — |
| Reactant | 4-methyl-6H,7H-thieno[3,2-c]pyridine | HCID 21821177 | — |
| Product | 4,5,8,9-tetrahydro-8-phenyl-7H-thieno[3,2-a]quinolizin-7-one | HCID 19020404 | — |
Reaction Steps
A mixture of 20 g of 6,7-dihydro-4-methyl-thieno[3,2-c]pyridine and 19.8 g of methyl 2-methylenephenylacetate was heated under an argon atomosphere to 80° for 2 hours and subsequently to 110° for 48 hours. Methanol was added to the cooled reaction mixture and the product was left to crystallize out. There was obtained 4,5,8.9-tetrahydro-8-phenyl-7H-thieno[3,2-a]quinolizin-7-one of m.p. 159°-161°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05036066 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-a4d697f75ea44f75b3c3748d60efe935 |
| Source note | uspto-grants-1991_07 |