HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 19773677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 3018436 | HCID 3018436 | — |
| Reactant | 3-Hydroxybutyl 4-methylbenzenesulfonate | HCID 13204323 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | HCID 19773677 | HCID 19773677 | 52% |
Reaction Steps
To a solution of 7.8 g of 3-[(4-hydroxy)phenyl]-5-hydroxymethyl-2-oxazolidinone (MD 760172) in 75 ml of methylethylketone, are added 10.2 g (0.074 mol) of K2CO3, 0.1 g of KI and 10.84 g (0.044 mol) of 3-hydroxy-1-butanol tosylate, the mixture is heated under reflux for 12 hours. After filtration, the reaction medium is concentrated and the product is obtained after chromatography (silica, eluent: CH2Cl2 : 92; CH3OH: 8) with a 52% yield,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05036091 |
| Source dataset | uspto-grants-1991_07 |
| ORD ID | ord-371b125bbf7441b893ebdcf5172943ac |
| Source note | uspto-grants-1991_07 |