Sodium Chloride → HCID 15030057, compound

Participants

Reaction Steps

To a solution of 1-acetoxy-1-cyclohexyl-1-phenylpropan-2-one (16.42 g, 0.06 mole) in 55 ml of a 90% aqueous methanol solution was added 3.2 g of potassium hydroxide. The solution was refluxed for 15 minutes, cooled, and 90 ml of a saturated aqueous sodium chloride solution was added. The reaction mixture was washed twice with ether. The ether washes were combined, dried and evaporated to dryness under vacuum. The crude product was vacuum distilled to afford a clear oil (10.51 g, 75.4%), bp 125°-8° C. (0.1 mm). NMR (CDCl3) δ7.6-7.2(m, 5H), 4.5(s, 1H), 2.1(s, 3H), 2.5-0.9(m, 11H). IR (neat) 3456, 3057, 1705, 1448, 1358, 1209, 1124 cm-1.

Provenance & Evidence