Water → 4-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

Participants

Reaction Steps

170 g of N-hexadecyl-3-nitro-4-chlorobenzenesulfonamide was dissolved in 640 ml of acetone. 79 g of potassium carbonate, 6 ml of polyethylene glycol, and 71 g of dimethyl sulfate were added to the solution. The admixture was heated under reflux for 5 hours. 240 ml of acetone was then added to the reaction system. 870 ml of water was added dropwise to the reaction system at a temperature of 40° C. The reaction system was allowed to cool to room temperature. As a result, crystals precipitated. The crystals were then filtered off, washed with water and methanol, and dried.

Provenance & Evidence