HRID1087673

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID24638

Chlorosulfuric acid

HClO3S

结构：C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CCC(=O)[C@@]3(C)CC[C@@]12O

HCID10425017

9α-hydroxyandrost-4-en-3,17-dione

C19H26O3

PRODUCTS

生成物

结构：C[C@]12CCC(=O)C=C1CC[C@@H]1C2=CC[C@]2(C)C(=O)CC[C@@H]12

HCID239595

9-Dehydroandrostenedione

C19H24O2

PROCEDURE

实验过程

Following the procedure of Example 2 but making noncritical variations 9α-hydroxyandrostenedione (10.00 g.) is reacted with chlorosulfonic acid to give androsta-4,9(11)-diene-3,17-dione, 9.01 g. (90.1% weight yield, 95.7% chemical yield).