HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphoric Acid → 9-Dehydroandrostenedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | 9alpha-Hydroxyandrost-4-ene-3,17-dione | HCID 10425017 | — |
| Solvent | Water | HCID 962 | — |
| Product | 9-Dehydroandrostenedione | HCID 239595 | — |
Reaction Steps
9α-Hydroxyandrostenedione (9.06 g.) is added to phosphoric acid (85%, 25 ml.) and stirred at 45°-55° for 24 hours. Water (75 ml.) is added, the mixture stirred for 2 hours and the solids are collected by filtration. The solids are washed with water (200 ml.) and air-dried to give androsta-4,9(11)-diene-3,17-dione, 8.11 g., (95.1% chemical yield); m.p. 193°-195°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE033364 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-c004e900d17244aca4f89d8fc4faef58 |
| Source note | uspto-grants-1990_10 |