Toluene → HCID 14328582, compound

Participants

Reaction Steps

A suspension of 47.4 g (0.133 mol) of methyltriphenyl-phosphonium bromide and 15.3 g (0.137 mol) of potassium tert.-butylate in 250 ml of absolute toluene is heated under reflux under dry nitrogen 25.2 g (0.1 mol) of 1-(4-chlorophenyl)-4,4,5-trimethyl-hexan-3-one are introduced over the course of 5 minutes The reaction mixture is heated under reflux for a further 15 hours, then cooled to room temperature, washed twice with water and concentrated under reduced pressure The residue is taken up in ethyl acetate, cooled to 5° C. and the crop of crystals formed is filtered off with suction. The filtrate is concentrated and distilled under reduced pressure. 14.5 g (58% of theory) of 2-(4-chlorophenylethyl)-3,3,4-trimethyl-pent-1-ene are obtained in the form of a yellow oil of boiling point 88°-90° C./0.1 mbar. ##STR22##

Provenance & Evidence