N,N,N',N'-Tetramethylmethanediamine → HCID 14556367, compound

Participants

Reaction Conditions

Reaction Steps

0.01 mole of 3-methyl-6-propionylbenzoxazolinone and 0.04 mole of bis(dimethylamino)methane are introduced into a 150-cm3 ground-necked flask equipped with a reflux condenser and a magnetic stirrer. 15 cm3 of acetic anhydride are added dropwise and the mixture is heated to 100° C. for 5 hours. After being cooled, the reaction mixture is poured into 5 volumes of ice-cold water. The mixture is acidified and stirred for one hour, and the product is drained, washed with water to neutrality, dried and recrystallized in hexane.

Provenance & Evidence