1-(2-Methoxyphenyl)piperazine → HCID 14556334, compound

HRID 1087749Notes

Reaction equation

HRID 1087749 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:15])[C:12](=[CH2:14])[CH3:13])=[CH:10][C:5]=2[O:4][C:3]1=[O:16].[CH3:17][O:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>CC(C)=O>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:11](=[O:15])[CH:12]([CH3:13])[CH2:14][N:28]3[CH2:27][CH2:26][N:25]([C:20]4[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=4[O:18][CH3:17])[CH2:30][CH2:29]3)=[CH:10][C:5]=2[O:4][C:3]1=[O:16]

Participants

4

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 14556367HCID 14556367, compound

Product 1

HCID 14556334HCID 14556334, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

100 cm3 of anhydrous acetone, 0.01 mole of 3-methyl-6-(2-methylenepropionyl)benzoxazolinone and 0.01 mole of 1-(2-methoxyphenyl)piperazine are introduced successively into a 250-cm3 ground-necked flask equipped with a reflux condenser and a magnetic stirrer. The mixture is brought to reflux for 6 hours and allowed to cool. The product is drained: the product of the title is obtained.

Workup

  1. customequipped with a reflux condenser and a magnetic stirrer
  2. temperatureto reflux for 6 hours
  3. temperatureto cool
  4. customthe product of the title is obtained

Sources & evidence

ORD record
ord-3f2d9ff8685d4e18b6e78eddd96ca048
Source dataset
uspto-grants-1990_10
Patent number
US04960778

Reaction notes

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