Tetrahydrofuran → HCID 14836222, compound

Participants

Reaction Steps

A dry 250 ml round bottom flask equipped with a nitrogen inlet, reflux condenser and stirring bar was charged with 2.44 g of 5-undecylhydantoin and 100 ml of THF. To this was added dropwise 10 ml of 3.5M Vitride in toluene. After the initial foaming had ceased the reaction mixture was refluxed for 30 hours. The reaction was quenched with saturated sodium sulfate solution and extracted with 3×50 ml of ether. The combined ether extracts were dried, filtered and concentrated. Recrystallization from ether gave 1.8 g (78%) of white crystals, m.p. 97°-99° C.

Provenance & Evidence