Methylhydroxylamine → HCID 14884263, compound

HRID 1087791Notes

Reaction equation

[CH3:1][N:2]([CH3:23])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]([CH3:16])=[CH:14][C:13](/[CH:17]=[CH:18]/[C:19](O)=[O:20])=[C:12]2[CH3:22])=[CH:7][CH:6]=1)=[O:4].[CH3:24][NH:25][OH:26]>>[CH3:1][N:2]([CH3:23])[C:3]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]([CH3:16])=[CH:14][C:13](/[CH:17]=[CH:18]/[C:19]([N:25]([OH:26])[CH3:24])=[O:20])=[C:12]2[CH3:22])=[CH:7][CH:6]=1)=[O:4]

Participants

Reactant 2

HCID 11647Methylhydroxylamine

HCID 14884268HCID 14884268, compound

Product 1

HCID 14884263HCID 14884263, compound

Procedure

(E)-3-[1-(4-Dimethylcarbamoylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-propenoic acid is condensed with N-methylhydroxylamine as described in example 1(a) to yield (E)-3-[1-(4-dimethylcarbamoylphenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-N-hydroxy-N-methyl-2-propenamide, m.p. 172°-174°.

Sources & evidence

ORD record: ord-b1e34b27c45d4162ae83b324dbee232c
Source dataset: uspto-grants-1990_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04960787

Reaction notes

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