HCID 4715345, compound → HCID 54266154, compound

HRID 1087797Notes

Reaction equation

HRID 1087797 reaction equation
C(N([CH2:9][CH:10]=[CH:11][C:12]1[CH:16]=[CH:15][N:14]([C:17]2[C:22]([CH3:23])=[CH:21][CH:20]=[CH:19][C:18]=2[CH3:24])[CH:13]=1)OC(=O)C)(=O)C.CC1C=CC=C(C)C=1N1C=CC(C=[O:39])=C1.C(OC(OCC)C(CC)(CC)P(O)(O)=O)C>>[CH3:24][C:18]1[CH:19]=[CH:20][CH:21]=[C:22]([CH3:23])[C:17]=1[N:14]1[CH:15]=[CH:16][C:12]([CH:11]=[CH:10][CH:9]=[O:39])=[CH:13]1

Participants

4

Reactant 3

HCID 4715345HCID 4715345, compoundHCID 53443046HCID 53443046, compoundHCID 54279475HCID 54279475, compound

Product 1

HCID 54266154HCID 54266154, compound

Procedure

Similarly prepared is N-acetyl-N-acetyloxy-3-[1-(2,6-dimethylphenyl)-1H-pyrrol-3-yl]-allylamine. The starting material is prepared by condensing 1-(2,6-dimethylphenyl)-1H-pyrrole-3-carboxaldehyde with diethyl phosphonoacetaldehyde diethylacetal to obtain 3-[1-(2,6-dimethylphenyl)-1H-pyrrol-3-yl]-acrolein. The aldehyde is then converted to the oxime and reduced to the hydroxylamine according to previously described procedures.

Workup

  1. customSimilarly prepared

Sources & evidence

ORD record
ord-aca7025e319f46c9ae9222edaef23f2f
Source dataset
uspto-grants-1990_10
Patent number
US04960787

Reaction notes

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