HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → HCID 14763469, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 1-(4-Bromophenyl)piperazine | HCID 2735629 | — |
| Reactant | N-[2-(Dimethylamino)ethyl]-4-(4-fluorophenyl)-1-piperazinecarboxamide | HCID 14763463 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 14763469 | HCID 14763469 | 84% |
Reaction Steps
This compound was prepared according to the procedure used to synthesize the compound of Example 11. A mixture of 4.8 g (0.03 mole) of 1,1'-carbonyldiimidazole, 2.6 g (0.03 mole) of unsym-dimethylethylenediamine, and 6.2 g (0.03 mole) of 1-(4-bromophenyl)piperazine in a total of 200 ml of tetrahydrofuran gave a pale yellow semisolid. The material was triturated with ethyl ether to give 7.7 g (84%) of the title compound as a white solid, m.p. 133°-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04960776 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-f133631483724e5b8152a372fd2ea627 |
| Source note | uspto-grants-1990_10 |