反应详情

A solution of 4',5,7-triacetoxy-2-methylisoflavone (5 g), benzoyl peroxide (0.3 g) and N-bromosuccinimide (3.9 g) in 300 ml carbon tetrachloride was heated under reflux for 12 hours, the solvent was distilled off under reduced pressure, water was added to the solid residue, the mixture was stirred well, and the crude product collected by filtration was recrystallized from a methanol/chloroform mixed solvent, affording 4.3 g of 4',5,7-triacetoxy-2-bromomethylisoflavone.

1. temperatureunder reflux for 12 hours
2. distillationthe solvent was distilled off under reduced pressure, water
3. additionwas added to the solid residue
4. filtrationthe crude product collected by filtration
5. customwas recrystallized from a methanol/chloroform mixed solvent