Ammonia → HCID 15598736, compound

HRID 1087964Notes

Reaction equation

HRID 1087964 reaction equation
[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19](OCC)=[O:20])=[CH:4][CH:3]=1.[NH3:26]>>[OH:1][C:2]1[CH:25]=[CH:24][C:5]([C:6]2[C:15](=[O:16])[C:14]3[C:9](=[CH:10][C:11]([OH:18])=[CH:12][C:13]=3[OH:17])[O:8][C:7]=2[C:19]([NH2:26])=[O:20])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 14459364HCID 14459364, compound

Product 1

HCID 15598736HCID 15598736, compound

Procedure

A mixture of ethyl 4',5,7-trihydroxy-2-isoflavonecarboxylate (120 mg) and 28% ammonia (2 ml) was stirred at room temperature for three hours, water was distilled off under reduced pressure, and the solid residue was recrystallized from methanol, affording 65 mg of 4',5,7-trihydroxy-2-isoflavonecarboxamide.

Workup

  1. distillationwater was distilled off under reduced pressure
  2. customthe solid residue was recrystallized from methanol

Sources & evidence

ORD record
ord-8b4834c0bf574e62b79ca9f84f232f02
Source dataset
uspto-grants-1990_10
Patent number
US04960908

Reaction notes

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