Silanol, 1,1,1-triethyl-, 1-acetate → Hexaethyldisiloxane

HRID 1088033Notes

Reaction equation

HRID 1088033 reaction equation
C([O:4][Si:5]([CH2:10][CH3:11])([CH2:8][CH3:9])[CH2:6][CH3:7])(=O)C.S[C:13]1[CH:18]=CN=CC=1>C(#N)C>[CH2:6]([Si:5]([O:4][Si:5]([CH2:6][CH3:7])([CH2:8][CH3:9])[CH2:10][CH3:11])([CH2:18][CH3:13])[CH2:8][CH3:9])[CH3:7]

Participants

4

Reactant 2

HCID 79173Silanol, 1,1,1-triethyl-, 1-acetateHCID 178418431pyridine-4-thiol

Product 1

HCID 70442Hexaethyldisiloxane

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To the resulting solution of mesylate (4) is added 4-mercaptopyridine (129 mg; 1.4 equivalents) and acetonitrile (2 ml) and stirred under ice cooling for 1 hour. The reaction mixture is poured into ice-water and adjusted at pH 6.0. The organic layer is separated, washed with aqueous sodium hydrogen carbonate and water, dried, and concentrated in vacuum to give pyridyl sulfide (7) as foamy residue.

Workup

  1. customThe organic layer is separated
  2. washwashed with aqueous sodium hydrogen carbonate and water
  3. customdried
  4. concentrationconcentrated in vacuum

Sources & evidence

ORD record
ord-56eb0b8120f74fbbb600a5525693f3d8
Source dataset
uspto-grants-1990_10
Patent number
US04960879

Reaction notes

Loading…