HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Pentanol → 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Pentanol | HCID 6276 | — |
| Reactant | HCID 12853597 | HCID 12853597 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione | HCID 12853599 | 69.3% |
Reaction Steps
A solution of 39.0 g (0.134 M) of 2,6-diaminoheptanedioic acid, dimethyl ester, dihydrochloride, 56 ml (0.4 M) of triethylamine, and 3 L of 1-pentanol was heated under reflux for 4 days. The solution was evaporated to dryness and the residue was recrystallized from chloroform to give 14.3 g of the title compound, mp 280°-3° (69%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962108 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-d3b8924a0acc4d31bb566751edae1d17 |
| Source note | uspto-grants-1990_10 |