HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,4S)-1-p-Nitrobenzyloxycarbonyl-2-(4-t-butyloxycarbonylbutyl)-4-acetylthiopyrrolidine → (2R,4S)-1-p-nitrobenzyloxycarbonyl-2-(4-carboxybutyl)-4-acetylthiopyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,4S)-1-p-Nitrobenzyloxycarbonyl-2-(4-t-butyloxycarbonylbutyl)-4-acetylthiopyrrolidine | HCID 15671523 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | (2R,4S)-1-p-nitrobenzyloxycarbonyl-2-(4-carboxybutyl)-4-acetylthiopyrrolidine | HCID 15671524 | — |
Reaction Steps
(2R,4S)-1-p-Nitrobenzyloxycarbonyl-2-(4-t-butyloxycarbonylbutyl)-4-acetylthiopyrrolidine (493 mg) was dissolved in 2.5 ml of trifluoroacetic acid, followed by stirring at room temperature for 15 minutes. The reaction mixture was distilled off to obtain (2R,4S)-1-p-nitrobenzyloxycarbonyl-2-(4-carboxybutyl)-4-acetylthiopyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04962103 |
| Source dataset | uspto-grants-1990_10 |
| ORD ID | ord-b76b80c2e41a4ce9bb00875e3ccf3f5c |
| Source note | uspto-grants-1990_10 |