Ethanol → HCID 14718890, compound

HRID 1088321Notes

Reaction equation

HRID 1088321 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[C:12]([F:13])=[C:11]([F:14])[C:7]([C:8](Cl)=[O:9])=[C:6]([F:15])[C:5]=1[F:16].[CH2:17]([OH:19])[CH3:18]>>[CH3:1][O:2][CH2:3][C:4]1[C:12]([F:13])=[C:11]([F:14])[C:7]([C:8]([O:19][CH2:17][CH3:18])=[O:9])=[C:6]([F:15])[C:5]=1[F:16]

Participants

3

Reactant 2

HCID 702EthanolHCID 14718889HCID 14718889, compound

Product 1

HCID 14718890HCID 14718890, compound

Procedure

The acid chloride from stage 1 (1.00 g) was dissolved in dry ethanol (5 cm3) and, when the initial exothermic reaction had subsided, the solution was stirred for a further 3 hours at the ambient temperature. The excess ethanol was evaporated under reduced pressure to yield ethyl 4-(methoxymethyl)-2,3,5,6-tetrafluorobenzoate (0.90 g) as a yellow oil.

Workup

  1. customwhen the initial exothermic reaction
  2. customThe excess ethanol was evaporated under reduced pressure

Sources & evidence

ORD record
ord-352310058ab7448c83300525cc40c729
Source dataset
uspto-grants-1990_10
Patent number
US04962109

Reaction notes

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